Conservative surgery for renal cell carcinoma--indications, technique and results.

J Base, J Navrátilová, A Mrázová, P Morávek, P Navrátil
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Abstract

At the Department of urology in Hradec Králové between 1989-1993 287 patients with a tumor of the kidney were operated on, in 45 of them (15.6%) conservatively. In this set there are 29 men and 16 women with the mean age 56.5 years. In 29 patients the contralateral kidney was normal (64%), 5 patients underwent nephrectomy for renal cell carcinoma, in 9 patients the opposite kidney was hypofunctionalised (hydronephrosis, cysts). In two patients the conservative approach was used for reasons of another type of malignancy (haematological). In 33 (73.3%) patients enucleation, in 12 patients resection of the lower or upper pole were done. The tumor was classified as T 1 stage in 6 patients, but in 4 patients already as T 3a (in patients with imperative indication). In 35 patients the tumor was moderately differentiated, in two ones with histologically confirmed renal cell carcinomas the tumors were poorly differentiated, in 8 patients there were histologically adenomas, in one angiomyolipoma and in another case scar after PCN (percutaneous nephrolithotomy). Preoperative examination included immunological examination, this was not done in two patients. Good results were obtained in 21 patients (60%), 12 patients were in high risk and 6 of them received immunotherapy. As an early complication one patient had urinary fistula, which resolved after introduction of stent. Relapse of malignancy in the screening period was not noticed.

肾细胞癌的保守手术——指征、技术和结果。
1989-1993年间,在hradc的泌尿科Králové, 287例肾脏肿瘤患者接受了手术,其中45例(15.6%)为保守手术。这组人中有29名男性和16名女性,平均年龄为56.5岁。29例对侧肾脏正常(64%),5例因肾细胞癌行肾切除术,9例对侧肾脏功能减退(肾积水、囊肿)。在两例患者中,由于另一种恶性肿瘤(血液学)的原因,采用了保守方法。在33例(73.3%)患者中,有12例患者切除了下极或上极。6例患者肿瘤分期为t1期,但4例患者已分期为t3a期(在有迫切适应症的患者中)。35例中分化,2例组织学证实肾细胞癌为低分化,8例组织学上有腺瘤,1例血管平滑肌脂肪瘤,1例经皮肾镜取石术后瘢痕。术前检查包括免疫学检查,2例患者未做免疫学检查。21例(60%)患者获得良好结果,12例为高危患者,其中6例接受免疫治疗。作为早期并发症,一名患者出现尿瘘,在引入支架后解决。筛查期未见恶性肿瘤复发。
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