[Quality assurance in preoperative autologous blood collection from the viewpoint of the anesthetist].

G Singbartl, W Schleinzer
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Abstract

From the anesthetist's point of view the following safety measures regarding autologous blood donation have to be considered: [1] inclusion/exclusion criteria for the patient's selection; [2] quality control of the autologous product itself and [3] adequate technical standards of the equipment applied. There is no doubt, the criteria used for the patient's selection of an autologous predeposit program have a great impact both on the number and the severity of complications that might occur. Anesthetists consider a patient eligible for an autologous predeposit program if he/she is considered eligible for an elective operative procedure, too; since this means that this patient demonstrates compensated organ functions (e.g. of the cardiovascular system, of the pulmonary function as well as of the metabolic and hematopoietic system). As shown by data in the literature, these criteria even hold true in patients with serious (but compensated) concomitant diseases. In contrast to the routine procedure of homologous donation, monitoring of a patient during the autologous predeposit procedure as well as an adequate replacement of the volume of the autologous predeposit donated appear to be reasonable, especially in patients with serious risk factors. Following this concept, the number of undesired side effects during the autologous donation is in the same order as it is known from healthy volunteers for homologous donation. It appears wise to apply the same safety and quality standards for an autologous predeposit as for the comparable homologous products. Most important and without any restriction, the autologous product has to be safe for the patient: there should be no bacterial contamination of the autologous product, and the corpuscular content of the autologous plasma should not exceed a definite limit.(ABSTRACT TRUNCATED AT 250 WORDS)

从麻醉师的角度看术前自体采血的质量保证。
从麻醉师的角度来看,必须考虑以下关于自体献血的安全措施:[1]患者选择的纳入/排除标准;[2]自身产品本身的质量控制和[3]所应用设备的足够的技术标准。毫无疑问,患者选择自体预沉积方案的标准对可能发生的并发症的数量和严重程度都有很大的影响。麻醉师认为,如果患者也有资格进行选择性手术,那么他/她也有资格进行自体预存手术;因为这意味着该患者表现出代偿的器官功能(例如心血管系统、肺功能以及代谢和造血系统)。正如文献数据所示,这些标准甚至适用于患有严重(但可补偿的)伴随疾病的患者。与常规的同源捐献相比,在自体预存过程中对患者进行监测,并充分替换捐献的自体预存容量似乎是合理的,特别是在有严重危险因素的患者中。根据这一概念,在自体捐赠过程中,不良副作用的数量与从健康志愿者中得知的同源捐赠的数量顺序相同。对自体预沉淀采用与同类产品相同的安全和质量标准似乎是明智的。最重要的是,在没有任何限制的情况下,自体产品必须对患者是安全的:自体产品不应有细菌污染,自体血浆的微粒含量不应超过一定的限制。(摘要删节250字)
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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