{"title":"Immunological relationship among rat erythrocyte membrane sialoglycoproteins and with human glycophorins.","authors":"A Herráez, A Díaz, J Luque, J C Díez","doi":"10.1016/0020-711x(93)90114-t","DOIUrl":null,"url":null,"abstract":"<p><p>1. Specific antibodies against a whole preparation of glycophorins from rat erythrocyte membrane and against its most prominent component (32 kDa) were prepared. 2. Both antisera and the respective affinity-purified antibodies recognize the 74, 32 and 25 kDa components of rat glycophorins; therefore, a close antigenic relationship between them can be inferred. 3. On the other hand, a cross-reaction with human glycophorin A (both MM- and NN-type) is observed for both antisera. 4. This suggests the existence of epitopes common to human and rat glycophorins.</p>","PeriodicalId":22539,"journal":{"name":"The International journal of biochemistry","volume":"25 7","pages":"1009-14"},"PeriodicalIF":0.0000,"publicationDate":"1993-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0020-711x(93)90114-t","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The International journal of biochemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/0020-711x(93)90114-t","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
1. Specific antibodies against a whole preparation of glycophorins from rat erythrocyte membrane and against its most prominent component (32 kDa) were prepared. 2. Both antisera and the respective affinity-purified antibodies recognize the 74, 32 and 25 kDa components of rat glycophorins; therefore, a close antigenic relationship between them can be inferred. 3. On the other hand, a cross-reaction with human glycophorin A (both MM- and NN-type) is observed for both antisera. 4. This suggests the existence of epitopes common to human and rat glycophorins.
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