Copper oxide powder as a copper supplement for sheep.

N A Cavanagh, G J Judson
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Abstract

The ability of oral doses of copper oxide powder to raise liver and blood copper concentration was examined in penned sheep given a pelleted diet containing 4 mg of copper per kg dry matter. Merino sheep of similar live weight and liver copper concentration were allocated at random to one of six treatment groups of four sheep each. Treatment groups received nil, 2.5 g, 5 g, 10 g, 20 g and 40 g of cupric oxide powder. The cupric oxide powder of sieve size 250-350 microns was effective in raising the liver copper concentration for at least 12 weeks. The large particles of oxide powder were retained in the gut for at least 13 days after dosing. Sheep given 10-40 g doses of cupric oxide powder were at risk of copper toxicity, as indicated by elevated plasma enzyme activities, liver copper concentrations and reduced liveweight gains. It was concluded that a 2.5 g dose of cupric oxide powder could be used to prevent short periods of copper deficiency in sheep at pasture without risk of copper toxicity.

氧化铜粉作为绵羊补铜剂。
在饲喂每千克干物质含4毫克铜的颗粒饲料的羊圈中,研究了口服氧化铜粉提高肝脏和血液中铜浓度的能力。选取活重和肝铜浓度相近的美利奴羊,随机分为6个处理组,每组4只羊。处理组给予0、2.5 g、5 g、10 g、20 g、40 g氧化铜粉。筛度为250 ~ 350 μ m的氧化铜粉能有效提高肝脏铜浓度至少12周。给药后,大颗粒的氧化物粉末在肠道中保留至少13天。绵羊被给予10-40克剂量的氧化铜粉,有铜中毒的风险,血浆酶活性升高,肝脏铜浓度升高,活重增加减少。由此可见,2.5 g氧化铜粉可预防牧场羊短时间缺铜,且无铜中毒风险。
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