{"title":"Molecular biology and clinical applications to cancer.","authors":"M T Lotze","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>New insights into the genetic changes associated with cancer, the genetic control of programmed cell death, and the availability of new tools to study biologic problems including targeted gene disruption and quantitative polymerase chain reaction have defined new questions and allowed more sophisticated answers in studies of fundamental cellular processes. The development of new approaches in the clinic, including nascent gene therapies, is rapidly evolving.</p>","PeriodicalId":79397,"journal":{"name":"Current opinion in general surgery","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current opinion in general surgery","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
New insights into the genetic changes associated with cancer, the genetic control of programmed cell death, and the availability of new tools to study biologic problems including targeted gene disruption and quantitative polymerase chain reaction have defined new questions and allowed more sophisticated answers in studies of fundamental cellular processes. The development of new approaches in the clinic, including nascent gene therapies, is rapidly evolving.