kdr-Type resistance in insects with special reference to the German cockroach, Blattella germanica

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry Pub Date : 1994-10-01 DOI:10.1016/0305-0491(94)90002-7

Jeffrey G. Scott, Ke Dong

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引用次数: 19

Abstract

The phenomenon of knockdown resistance (kdr) was first noted in the housefly (Musca domestica), and has subsequently be found (i.e. kdr-type resistance) in several other insect pests including the German cockroach (Blattella germanica). This type of resistance causes insensitivity of the nervous system to pyrethroids, DDT and a limited number of sodium channel neurotoxins. In the German cockroach, kdr-type resistance is incompletely recessive, monogenic and not sex linked or due to cytoplasmic factors. Additionally, kdr-type resistance is not associated with a change in sodium channel density, kdr or kdr-type loci are tightly linked or identical to the para-homologous sodium channel locus in German cockroach, housefly and tobacco budworm (Heliothis virescens), suggesting that kdr and kdr-type resistance are due to mutations in the para-homologous sodium channel gene. kdr-Type resistance in the German cockroach appears similar, although not necessarily identical, to kdr in houseflies.

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昆虫对kdr型的抗性，特别涉及德国小蠊

首先在家蝇(Musca domestica)中发现了击倒抗性(kdr)现象，随后在包括德国小蠊(Blattella germanica)在内的其他几种害虫中也发现了击倒抗性(即kdr型抗性)。这种类型的抗性导致神经系统对拟除虫菊酯、滴滴涕和有限数量的钠通道神经毒素不敏感。在德国蜚蠊中，kdr型抗性是不完全隐性的，单基因的，与性别无关或由细胞质因素引起。此外，kdr型抗性与钠通道密度的变化无关，kdr或kdr型位点与德国蜚蠊、家蝇和烟草budworm (Heliothis virescens)的准同源钠通道位点紧密相连或相同，表明kdr和kdr型抗性是由准同源钠通道基因突变引起的。德国蟑螂的kdr型抗性与家蝇的kdr型抗性相似，但不一定完全相同。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Comparative Biochemistry and Physiology Part B: Comparative Biochemistry

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