Balloon pulmonary valvuloplasty for isolated pulmonary valvular stenosis.

L Mattioli, J M Belmont, K Goertz, R Ardinger
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Abstract

Fifteen balloon pulmonary valvuloplasties (BPVs) were performed on 13 infants and children with isolated pulmonary valvular stenosis (PVS). There were no complications. Two patients required repeat BPV, one for failure, the other for restenosis. At the time of the 13 latest BPVs, age ranged from three days to 13.1 years (mean 5.7 +/- SD 4.8 years). Average Doppler pulmonary valve pressure gradient preceding BVP was 75 +/- 22 mm Hg. At follow-up it was 25 +/- 9 mm Hg (p < .0001). Follow-up interval was 0.61 to 4.70 years (2.29 +/- 1.18). Restenosis occurred in 1/13 (8%) of the patients. The remaining 12/13 (92%) showed highly satisfactory sustained gradient reductions. Doppler gradients preceding BPV by as much as 4 months correlated highly with catheter gradients at time of BPV, confirming that Doppler echocardiography is a highly accurate indication of PVS severity. Catheterization for PVS should therefore not be used for diagnostic purposes alone. BPV can be performed safely, economically and effectively and is recommended as the treatment of choice for infants and children with moderate to severe isolated PVS. For very young patients, follow-up Doppler surveillance should be done semi-annually; for all others, annually.

球囊肺动脉瓣成形术治疗孤立性肺动脉瓣狭窄。
本文对13例孤立性肺瓣膜狭窄(PVS)患儿行球囊肺瓣膜成形术15例。没有并发症。2例患者需要重复BPV, 1例失败,另1例再狭窄。在最近13例bpv发生时,年龄从3天到13.1岁不等(平均5.7±4.8岁)。BVP前平均多普勒肺动脉瓣压力梯度为75 +/- 22 mm Hg,随访时为25 +/- 9 mm Hg (p < 0.0001)。随访时间为0.61 ~ 4.70年(2.29±1.18)。1/13(8%)的患者发生再狭窄。其余12/13(92%)显示出非常满意的持续梯度降低。BPV前的多普勒梯度与BPV时的导管梯度高度相关,证实了多普勒超声心动图是PVS严重程度的高度准确指示。因此,PVS的导管置入不应仅用于诊断目的。BPV可以安全、经济和有效地进行,并被推荐作为中度至重度孤立性pv的婴儿和儿童的治疗选择。对于非常年轻的患者,应每半年进行一次多普勒随访监测;其他的,每年一次。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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