[The effect of training and anabolic agents on the weight of the heart and extremities].

Abstract

Albino-mice (50 animals per group) were exercised (running) for 30 days (29,6 km/animal totally) or received in the same period Methandrostenolon (0,12 mg/animal). With a third group exercise and anabolic steroid was combined. Mean body weight, mean weight of fore and hind leg, also mean weight of heart were compared between the groups and with corresponding weights of the control group. Calculating with allometry equation the influence of both exogen factors on weight of extremities and weight of heart was determined. Anabolic steroid resulted an increased body weight, significantly more than in the control animals. Exercise reduced statistically the weight of living animals. Without influence of body weight the combination of exercise and anabolic steroid made an increase to the weight of extremities, especially of the hind leg. The weight of heart increased only after exercise.