V I Shamaev, T V Krutova, R F D'yachkovskaya, D B Korman, O S Shkrob, N A Kuznetsov
{"title":"The effect of diazane on the proliferation of human tumor cells.","authors":"V I Shamaev, T V Krutova, R F D'yachkovskaya, D B Korman, O S Shkrob, N A Kuznetsov","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The effect of the antitumorigenic agent diazane (1,2-bis-diazoacetylethane) in the cells of 30 human tumors cultured in vivo in diffusion chambers, implanted intraperitoneally into mice. Twenty-four hours after the introduction of diazane, a decrease in the proportion of DNA-synthesizing cells and the intensity of DNA synthesis to 30--50% of the control values is observed. By 48 hours, the values of these parameters had returned to the initial level.</p>","PeriodicalId":9166,"journal":{"name":"Biology bulletin of the Academy of Sciences of the USSR","volume":"8 2","pages":"171-6"},"PeriodicalIF":0.0000,"publicationDate":"1981-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biology bulletin of the Academy of Sciences of the USSR","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The effect of the antitumorigenic agent diazane (1,2-bis-diazoacetylethane) in the cells of 30 human tumors cultured in vivo in diffusion chambers, implanted intraperitoneally into mice. Twenty-four hours after the introduction of diazane, a decrease in the proportion of DNA-synthesizing cells and the intensity of DNA synthesis to 30--50% of the control values is observed. By 48 hours, the values of these parameters had returned to the initial level.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
