Urinary free cortisol excretion in endogenously depressed and schizophrenic patients.

K Diebold, H Kick, G Schmidt
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引用次数: 6

Abstract

In 8 endogenously depressed and 9 schizophrenic patients, the excretion of urinary free cortisol was measured. The endogenous depressives exhibited a significantly (p less than 0.01) higher excretion of free cortisol (X = 122 microgram/24 h or X = 68 microgram/24 h) when compared to schizophrenics. This finding, earlier reported by others, suggests a hypothalamic-pituitary-adrenocortical activation in endogenously depressed patients.

内源性抑郁症和精神分裂症患者尿中游离皮质醇的分泌。
测定8例内源性抑郁症患者和9例精神分裂症患者尿中游离皮质醇的排泄量。与精神分裂症患者相比,内源性抑郁症患者的游离皮质醇排泄量(X = 122微克/24小时或X = 68微克/24小时)显著增加(p < 0.01)。这一发现早前被其他人报道,表明内源性抑郁症患者存在下丘脑-垂体-肾上腺皮质激活。
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