Ovarian tumors in children and adolescents less than 20 years age.

M Yakushiji, T Matsukuma, M Abe, T Nishida, H Nishimura, A Tsunawaki, T Kato
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Abstract

Reports are made of the analytical results of 76 cases with ovarian neoplasma under 20 years of age who had been treated at the Kurume University Hospital from January 1952. The incidence of ovarian tumors was 5.5% in all age groups, and the youngest patient was 5 years of age, the mean age being 15 years. Histologically, these tumors comprised 48 cases (63%) of germ cell origin, showing characteristically of ovarian tumors occurring in childhood and adolescence. The total 76 cases included 40 of malignant tumors, which were subdivided into 13 of embryonal carcinoma, 12 of solid teratoma, 9 of dysgerminoma, 5 of simple carcinoma, and 1 case of granulosa cell tumor. In all the cases the clinical stage was important factor for prognosis, and the prognosis of embryonal carcinoma was poorest, with only 4 cases of survival out of 13 cases. But the prognosis of dysgerminoma was comparatively good, with 8 cases of survival out of 9 cases. It is worthy of note that this tumor was highly radiosensitive, since 3 out of 4 cases at stage III and stage IV had been surviving for over 5 years.

20岁以下儿童和青少年的卵巢肿瘤。
本文报告了1952年1月以来在库鲁姆大学医院治疗的76例20岁以下卵巢肿瘤患者的分析结果。各年龄组卵巢肿瘤的发生率为5.5%,年龄最小的为5岁,平均年龄为15岁。组织学上,这些肿瘤包括48例(63%)生殖细胞起源,表现出发生在儿童和青少年的卵巢肿瘤的特征。共76例,其中恶性肿瘤40例,其中胚胎癌13例,实体畸胎瘤12例,无生殖细胞瘤9例,单纯性癌5例,颗粒细胞瘤1例。临床分期是影响预后的重要因素,其中胚胎癌预后最差,13例中仅有4例存活。但无生殖细胞瘤的预后较好,9例中有8例存活。值得注意的是,该肿瘤具有高度的放射敏感性,因为3 / 4的III期和IV期患者存活超过5年。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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