[Changes in the thymic factor level in rats with Jensen sarcoma and modification of the rate of tumor growth by administration of thymic hormone].

Abstract

Rats were differently treated after transplantation of cells of Jensen sarcoma to test the influence of Doparkin (increase of the cAMP level), morbilli vaccine (interferon inductor) and local radio-therapy alone or in combination for a decrease of the rate of growing tumors. The lowest rate of growing tumors was received by combining the agents with a local radio-therapy. The analysis of the thymic factor level showed in the animals with a tumor a significant reduction in comparison to normal animals respectively to animals without tumor formation in consequence of the therapy. An application of the thymic factor alone respectively in combination with Doparkin and morbilli vaccine leads to a clear decrease of the rate of growing tumors.