Cytotoxic activity and progesterone binding capacity of maternal lymphocytes are not influenced by gestational age and by the number of previous pregnancies.

J Szekeres, V Csernus, J Hadnagy, A S Pácsa
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Abstract

Cytotoxic activity and progesterone binding capacity of lymphocytes obtained from 135 pregnant women was tested. Cytotoxic activity of healthy pregnant women's lymphocytes was significantly lower (p less than 0.001), while progesterone binding capacity significantly higher (p less than 0.001), than those of lymphocytes obtained from women with threatened abortion or threatened premature labour. Neither cytotoxic activity nor progesterone binding capacity of the lymphocytes was influenced by gestational age. Furthermore, the number of previous pregnancies did not have any effect on either of the two parameters.

母体淋巴细胞的细胞毒活性和孕酮结合能力不受胎龄和妊娠次数的影响。
测定了135例孕妇淋巴细胞的细胞毒活性和孕酮结合能力。健康孕妇淋巴细胞的细胞毒活性显著低于先兆流产或先兆早产妇女的淋巴细胞(p < 0.001),而孕酮结合能力显著高于先兆流产或先兆早产妇女的淋巴细胞(p < 0.001)。细胞毒活性和孕酮结合能力均不受胎龄的影响。此外,以前怀孕的次数对这两个参数都没有任何影响。
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