Clinical features and course of IgA glomerulonephritis.

J Nagy, H Brasch, C Trinn, T Burger
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Abstract

A review of the clinical features, laboratory findings and course in 50 cases of IgA glomerulonephritis confirmed by biopsy is presented. The onset and clinical course of the process was oligosymptomatic in the majority of the cases with a predominance of microhematuria and persistent proteinuria. By the end of the observation period more than 50 per cent of the patients became hypertensive and in 16 cases serum creatinine levels attained 132 mumol/l (1.5 mg per 100 ml) or more. Proteinuria in excess of 1 g/24h, hypertension and an impaired concentration capacity at the onset heralded early progression.

IgA肾小球肾炎的临床特点及病程。
本文回顾了50例经活检证实的IgA肾小球肾炎的临床特点、实验室检查结果和病程。大多数病例的发病和临床过程无明显症状,以微量血尿和持续性蛋白尿为主。在观察期结束时,超过50%的患者成为高血压,16例患者血清肌酐水平达到132 μ mol/l(每100毫升1.5 mg)或更高。蛋白尿超过1克/24小时,高血压和发病时的集中能力受损预示着早期进展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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