Multisystem presentation of eosinophilic fasciitis.

D Caspi, R Fishel, M Varon, E Yona, M Baratz, M Yaron
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引用次数: 23

Abstract

A 20-year-old man experienced the onset of progressive scleroderma-like skin changes with eosinophilia and hypergammaglobulinaemia after strenuous military activity. A biopsy showed faciitis. Concomitant splenomegaly, polysynovitis, restrictive lung function, myositis, decrease hepatic clotting factors and proteinuria were documented. He responded well to corticosteroids, relapse upon their discontinuation and had a complete remission of both skin and systemic features while on penicillamine and azathioprine. He is new in good health and has received no medication for the past two years.

嗜酸性筋膜炎的多系统表现。
一位20岁的男性在剧烈的军事活动后出现进行性硬皮病样皮肤变化,伴有嗜酸性粒细胞增多和高γ -球蛋白血症。活检显示面部炎。同时伴有脾肿大、多滑膜炎、肺功能受限、肌炎、肝凝血因子减少和蛋白尿。他对皮质类固醇反应良好,停药后复发,在使用青霉胺和硫唑嘌呤时皮肤和全身特征完全缓解。他现在身体很好,过去两年没有接受任何药物治疗。
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