Neuroendocrinological aspects of depression and symptomatological picture.

P Tosca, L Fenoglio, F Zerbi, A Romani, G Bezzi, E Ferrari, C Canepari
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引用次数: 7

Abstract

Cortisol and prolactin circadian rhythms were determined in a group of depressed hospitalized women who were submitted the next day to the dexamethasone suppression test. The depressed were classified as endogenous and non-endogenous according to symptomatological criteria. Some significant differences were found between the two groups when compared to control subjects in cortisol as well as prolactin biorhythms, and the cortisol suppression percentages were significantly lower in the endogenous than in the non-endogenous. This difference is abolished by benzodiazepine treatment.

抑郁症的神经内分泌方面和症状学图片。
在一组抑郁的住院妇女中测定皮质醇和催乳素昼夜节律,这些妇女在第二天接受地塞米松抑制试验。根据症状标准将抑郁分为内源性和非内源性。与对照组相比,两组在皮质醇和催乳素生物节律方面存在显著差异,内源性皮质醇抑制百分比明显低于非内源性。这种差异通过苯二氮卓类药物治疗而消除。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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