[Study of GH in patients suffering from sexual impotence and abnormal glucose tolerance test (author's transl)].

P Chiodera, R Volpi, G Zanardi, D Michelini, G Caffarri, C Canetti, E Bruni, A Caiazza, P P Vescovi, A Pezzarossa, E Tarditi
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Abstract

The correlation between dopamine-serotonin systems and sexual behaviour and the influence of these two amines on GH secretion is well known. We evaluated GH responses (maximum increase (delta) after OGTT and mean increase (delta M) after insulin test) in a group of 32 males suffering from erective impotence with impotence with abnormal reaction to a glucose tolerance test. Results were compared with those obtained in a group of 13 normal controls. No significant difference in basal values and dynamic responses between the two groups was present. Our data suggest that GH doesn't decrease the tolerance to glucose in these patients. The abnormal values observed during a glucose tolerance test may be due to some agent involved in the interactions between limbic system, ventral lateral and ventral medial hypothalamic nuclei and dopamine-serotonin systems. No influence by this system on GH secretion is evident.

[阳痿和糖耐量异常患者生长激素的研究(作者译)]。
多巴胺-血清素系统与性行为之间的相关性以及这两种胺对生长激素分泌的影响是众所周知的。我们评估了32名阳痿患者的生长激素反应(OGTT后的最大增加(delta)和胰岛素试验后的平均增加(delta M)),这些阳痿患者对葡萄糖耐量试验反应异常。结果与正常对照组13例进行比较。两组之间的基础值和动态反应无显著差异。我们的数据表明生长激素不会降低这些患者对葡萄糖的耐受性。在葡萄糖耐量试验中观察到的异常值可能是由于某些因素参与了边缘系统、下丘脑腹侧核和腹侧内侧核以及多巴胺-血清素系统之间的相互作用。这个系统对生长激素分泌没有明显的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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