[Haemophilus influenzae: sensitivity to 12 antibiotics, analysis according to capsular serotype, biotype and source of isolation, and epidemiologic implications].

Annales de microbiologie Pub Date : 1982-11-01
G Pinon
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Abstract

A total of 129 strains of Haemophilus influenzae were tested for susceptibility to twelve antibiotics. Capsular serotypes and biotypes were determined, and the relation between these parameters and minimal inhibitory concentrations (MIC) were analysed. Non-capsulated strains were more susceptible to streptomycin than capsulated ones. The distribution of MIC of chloramphenicol among biotypes was different. The distribution of MIC of penicillin G, tetracycline and chloramphenicol among sources of isolation was also different. Therefore the strains did not have the same origin, and one should look at the concept of organotropism for H. influenzae.

[流感嗜血杆菌:对12种抗生素的敏感性,根据荚膜血清型、生物型和分离来源进行分析,以及流行病学意义]。
对129株流感嗜血杆菌进行了12种抗生素的药敏试验。测定荚膜血清型和生物型,并分析这些参数与最低抑菌浓度(MIC)的关系。未荚膜菌株对链霉素的敏感性高于荚膜菌株。氯霉素的MIC在不同生物型间分布不同。青霉素G、四环素和氯霉素的MIC在不同分离源间的分布也不同。因此,菌株不具有相同的起源,人们应该考虑流感嗜血杆菌的器官亲和性概念。
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