The transport of plasma lipids: basic and clinical research and relationship to coronary heart disease.

Abstract

Research on the physiology and medical importance of the plasma lipids is a rapidly evolving field. Recent developments may have pointed the way to a future understanding of the chemistry of lipid-protein interactions, the clearance of atherogenic particles, the metabolic interactions between lipoproteins, and the regulation of lipid modifying enzymes. Along with basic research of this type, clinical trials now in progress may lead to much-needed insights into the epidemiology and prevention of clinical disease.