Pancreatic tissue pH in experimental acidosis and alkalosis.

S Farkas, J Lantos, G Halmágyi, Z Molnár
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Abstract

The pH was studied in pancreatic tissue and arterial blood in 22 dogs. Respiratory acidosis was induced by CO2 inhalations in 5 dogs, respiratory alkalosis by hyperventilation in 5 dogs, metabolic acidosis by intravenous(i.v.) infusion of 0.1 N HCl in 5 dogs, metabolic alkalosis by i.v. infusion of 4.2% Na bicarbonate in 5 dogs. The differences between the shifts of blood pH and tissue pH were not significant statistically. Infusion of Ringer's solution failed to affect the pH in blood and pancreatic tissue in two control animals. It is concluded, that with an adequate tissue blood flow the pancreatic tissue pH is uninformative unless the blood pH is known.

实验性酸中毒和碱中毒的胰腺组织pH值。
研究了22只狗胰腺组织和动脉血的pH值。5只狗通过吸入二氧化碳引起呼吸性酸中毒,5只狗通过过度换气引起呼吸性碱中毒,5只狗通过静脉滴注0.1盐酸引起代谢性酸中毒,5只狗通过静脉滴注4.2%碳酸氢钠引起代谢性碱中毒。血液pH值与组织pH值变化差异无统计学意义。在两个对照动物中,输林格氏液对血液和胰腺组织的pH值没有影响。结论是,在组织血流量充足的情况下,除非已知血液pH值,否则胰腺组织pH值是没有意义的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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