[Level of polysomes in cells of Escherichia coli treated with sublethal doses of aminoglycosides].

J C Cortay, J Marchal, A Cozzone
{"title":"[Level of polysomes in cells of Escherichia coli treated with sublethal doses of aminoglycosides].","authors":"J C Cortay,&nbsp;J Marchal,&nbsp;A Cozzone","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Polysome level was measured in Escherichia coli cells grown in the presence of sublethal doses of four different aminoglycosides which all induce mistranslation: streptomycin, neomycin, kanamycin and gentamycin. No significant variation was noticed as referred to the level of polysomes in normally growing cells. This observation indicates that the erroneous incorporation of amino acids into polypeptide chains does not necessarily result in the release of ribosomes from messenger RNA molecules.</p>","PeriodicalId":10605,"journal":{"name":"Comptes rendus des seances de l'Academie des sciences. Serie D, Sciences naturelles","volume":"291 5","pages":"473-6"},"PeriodicalIF":0.0000,"publicationDate":"1980-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Comptes rendus des seances de l'Academie des sciences. Serie D, Sciences naturelles","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Polysome level was measured in Escherichia coli cells grown in the presence of sublethal doses of four different aminoglycosides which all induce mistranslation: streptomycin, neomycin, kanamycin and gentamycin. No significant variation was noticed as referred to the level of polysomes in normally growing cells. This observation indicates that the erroneous incorporation of amino acids into polypeptide chains does not necessarily result in the release of ribosomes from messenger RNA molecules.

[亚致死剂量氨基糖苷处理大肠杆菌细胞中的多聚体水平]。
在四种不同氨基糖苷的亚致死剂量下生长的大肠杆菌细胞中测量了多体水平,这四种氨基糖苷均可诱导误翻译:链霉素、新霉素、卡那霉素和庆大霉素。在正常生长的细胞中,聚体的水平没有明显的变化。这一观察结果表明,氨基酸在多肽链中的错误结合并不一定导致信使RNA分子释放核糖体。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信