[IgM class antibodies against hepatitis A viruses in the differentiation of viral hepatitis].

V Zivanović-Marinković, D Stanković, S Parabucki, A Lazarov, V Marinković, L Krstić, Z Letica
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Abstract

The sera of 64 patients with acute viral hepatitis which were previously HbsAG negative by rPHA were tested by RIA methods for the presence of HBsAG and anti-HBc, by EIA method for HBc and anti-HBc and also by RIA method for the presence of IgM antibodies against hepatitis A virus. The pairs of sera were tested also for the presence of antibodies against cytomegalovirus and EB viruses. Of the total of 64 patients, markers of fresh HB viral infection were proved in 5 patients, sera positive to IgM antibodies to hepatitis A virus were found in 51 and no positive tests to any of the tested viruses were found in 8. The authors consider that they belonged to "non-A, non-B" viral hepatitis.

[抗甲型肝炎病毒IgM类抗体在病毒性肝炎鉴别中的应用]。
对64例经rPHA检测HbsAG阴性的急性病毒性肝炎患者,采用RIA法检测HbsAG和抗HBc, EIA法检测HBc和抗HBc, RIA法检测抗甲型肝炎病毒IgM抗体的存在。对血清进行巨细胞病毒和EB病毒抗体检测。在64例患者中,5例患者被证实为新鲜HB病毒感染标志物,51例患者血清中发现甲型肝炎病毒IgM抗体阳性,8例患者未发现任何检测病毒阳性。作者认为他们属于“非甲、非乙”病毒性肝炎。
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