Relationship of CSF shunting and IQ in children with myelomeningocele: a retrospective analysis.

Child's brain Pub Date : 1984-01-01 DOI:10.1159/000120166
T B Mapstone, H L Rekate, F E Nulsen, M S Dixon, N Glaser, M Jaffe
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引用次数: 51

Abstract

This paper reviews 75 infants with myelomeningocele treated either at birth or from an early age at Rainbow Babies and Children's Hospital, for whom complete records and psychometric testing (IQ) are available (including complete summaries from referring hospitals). Three groups are compared: (1) infants without complications who were shunted for hydrocephalus (n = 41); (2) infants with complications who were shunted (n = 16), and (3) infants who were not shunted (n = 18). Complications were defined as ventriculitis (positive CSF cultures with elevated protein, depressed glucose and inflammatory cells), anoxia, poorly controlled hydrocephalus or other CNS anomalies such as porencephaly. The mean IQ of infants who were not shunted was 104, of those shunted without complications it was 91, and of those shunted who had complications it was 70. These IQ differences were significant at p less than 0.01, and were not explained by differences in spinal lesion levels.

脊髓脊膜膨出患儿脑脊液分流与智商的关系:回顾性分析。
本文回顾了75名在彩虹婴儿和儿童医院出生或早期治疗的脊髓脊膜膨出婴儿,他们的完整记录和心理测量测试(智商)是可用的(包括转诊医院的完整摘要)。三组比较:(1)无并发症的婴儿因脑积水行分流术(n = 41);(2)合并并发症的分流婴儿(n = 16),(3)未分流婴儿(n = 18)。并发症定义为脑室炎(脑脊液培养阳性,蛋白升高,葡萄糖和炎症细胞下降),缺氧,控制不佳的脑积水或其他中枢神经系统异常,如脑孔畸形。没有分流的婴儿的平均智商是104,分流没有并发症的是91,分流有并发症的是70。这些智商差异在p < 0.01时具有显著性,并且不能用脊髓损伤程度的差异来解释。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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