Bioconversions of a macrolide glycoside by growing L-form cells of Streptomyces hygroscopicus.

Abstract

Growing L-form cells of Streptomyces hygroscopicus were shown to carry out 3-0-acylation and 14-C-hydroxylation of a macrolide glycoside suggesting that both types of bioconversion do neither require the intact cell wall nor the periplasmic space.