[Modern diagnosis and prognosis in isoimmunization in the Rh system].

Abstract

A total of 118 Rh isoimmunized pregnant women were discovered from 1972 to 1981. In diagnosing the disorder, the author draws attention to the examination of bilirubin in the amnionic fluid as the most reliable indicator, to which the dosing of measurable antibodies and echography are, in his opinion, a precious contribution. The administration of corticosteroids, antihistaminics, capillary protectors, and sedatives proved unreliable. A premature delivery was induced in 79 cases, after the assessment of the fetus maturity. The pregnancy was terminated vaginally in 60 and by cesarean section in 19 cases. Twenty-two near-term children ere delivered without major problems. Failure was recorded in 31 (26.3%) cases: 17 deaths in the uterus and 14 deaths of newborns immediately after birth. Out of 87 surviving children, 36 received exsanguinotransfusion 1-4 times.