G Sassolas, H Rousset, R Cohen, P Chatelain, B Claustrat, S Laporte, B Laferrère, A El Charfi, S Ferry
{"title":"[Somatocrinin induces growth hormone release in a case of growth hormone deficiency of hypothalamic origin in a child].","authors":"G Sassolas, H Rousset, R Cohen, P Chatelain, B Claustrat, S Laporte, B Laferrère, A El Charfi, S Ferry","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Somatocrinin (hp-GRF-44), a growth hormone releasing factor, stimulates acute pituitary response in a 11 years and 4 months old boy, with growth hormone deficiency. The capability of the anterior pituitary to secrete growth hormone in response to an IV injection of somatocrinin (120 micrograms 4 micrograms/kg) was documented, therefore proving the hypothalamic origin of the deficit which had been suspected because of association of diabetes insipidus and hyperprolactinemia.</p>","PeriodicalId":10622,"journal":{"name":"Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie","volume":"296 11","pages":"527-30"},"PeriodicalIF":0.0000,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Somatocrinin (hp-GRF-44), a growth hormone releasing factor, stimulates acute pituitary response in a 11 years and 4 months old boy, with growth hormone deficiency. The capability of the anterior pituitary to secrete growth hormone in response to an IV injection of somatocrinin (120 micrograms 4 micrograms/kg) was documented, therefore proving the hypothalamic origin of the deficit which had been suspected because of association of diabetes insipidus and hyperprolactinemia.