[Release in secondary mixed leukocyte cultures of a factor inducing citrulline production by bone marrow cells].

Abstract

Citrulline production is demonstrated in murine bone marrow cell cultures incubated with dialyzed secondary MLC supernatant. This synthesis, proceeding from arginine, is induced by a soluble protein factor released during secondary MLC, unstable to heat, with a molecular weight of approximately 150,000 daltons.