{"title":"Cholera and cell regulation.","authors":"M Vaughan","doi":"10.1080/21548331.1982.11702338","DOIUrl":null,"url":null,"abstract":"<p><p>The cholera vibrio, unlike most pathogens, neither invades the body's cells nor causes them direct physical damage and thus does not engender inflammation or fever. Rather, the organism attaches itself to the intestinal epithelium, where it secretes a toxin that deranges cellular function. Study of the toxin's structure and mechanism of action is helping to elucidate normal enzymatic processes.</p>","PeriodicalId":79221,"journal":{"name":"Hospital practice (Hospital ed.)","volume":"17 6","pages":"145-52"},"PeriodicalIF":0.0000,"publicationDate":"1982-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/21548331.1982.11702338","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hospital practice (Hospital ed.)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/21548331.1982.11702338","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The cholera vibrio, unlike most pathogens, neither invades the body's cells nor causes them direct physical damage and thus does not engender inflammation or fever. Rather, the organism attaches itself to the intestinal epithelium, where it secretes a toxin that deranges cellular function. Study of the toxin's structure and mechanism of action is helping to elucidate normal enzymatic processes.
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