Application of high-performance liquid chromatography to abnormal hemoglobin studies

Biochimica et Biophysica Acta (BBA) - Protein Structure Pub Date : 1981-09-29 DOI:10.1016/0005-2795(81)90010-6

Jean-Paul Boissel , Henri Wajcman , Hubert Fabritius , Raymond Cabannes , Dominique Labie

引用次数: 15

Abstract

A strategy is reported which allows the rapid characterization of different hemoglobins D found in Ivory Coast. It involves reverse-phase HPLC for peptide separations and micro-sequencing by the manual solid-phase method of Chang. Identification of hemoglobin Avicenna, hemoglobin Korle Bu and hemoglobin Cocody, a new variant (β 21 (B3) Asp → Asn), is described.

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高效液相色谱法在异常血红蛋白研究中的应用

报告了一种策略，可以快速表征科特迪瓦发现的不同血红蛋白D。它包括反相高效液相色谱法的肽分离和微测序的手工固相法的Chang。本文报道了蛋白Avicenna、蛋白Korle Bu和蛋白Cocody新变异(β 21 (B3) Asp→Asn)的鉴定。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Biochimica et Biophysica Acta (BBA) - Protein Structure

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