Effect of beta-blocking agents on the increased serum gastrin levels in hyperthyroidism.

J Földes, C Bános, J Borvendég
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Abstract

In a number of hyperthyroid patients the serum gastrin level exceeds the normal range. Administration of beta-blocking agents results in a decrease of the hypergastrinaemia. The fall in the serum gastrin levels is unrelated to the effect of beta-blocking agents on peripheral thyroxine metabolism, but is associated with a decline of the plasma cAMP levels. It is suggested that, though beta adrenergic sensitivity is one of the factors of hypergastrinaemia in hyperthyroidism, other factors may be involved in its production, too.

阻滞剂对甲亢患者血清胃泌素水平升高的影响。
在一些甲亢患者中,血清胃泌素水平超过正常范围。β -阻滞剂的施用导致高胃血症的减少。血清胃泌素水平的下降与β -阻断剂对外周甲状腺素代谢的影响无关,但与血浆cAMP水平的下降有关。提示,虽然肾上腺素能敏感性是甲亢患者高胃泌素血症的因素之一,但其产生也可能与其他因素有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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