Identification of a protein (p40x) encoded by a unique sequence pX of human T-cell leukemia virus type I.

Abstract

A protein p40x was identified as a product encoded by frame IV in the pX region of human T-cell leukemia virus type I. Sera from patients with adult T-cell leukemia contained antibodies against p40x, indicating its expression in vivo. The occurrence of splicing to form pX mRNA is proposed and the possible significance of p40x is discussed.