{"title":"Congenital toxoplasmosis and deafness. An investigation.","authors":"I Wright","doi":"10.1159/000275019","DOIUrl":null,"url":null,"abstract":"In conclusion, it may be said that congenital toxo-plasmosis as a cause of deafness is unlikely in man; it could not be said to be impossible. Acceptable criteria for such a diagnosis are difficult to see [Wright, 1971]. Low antibodies in the mother might be a factor in favour of transmission; high antibodies and evidence of infection during the relevant pregnancy would most likely lead to a classical case of congenital toxoplasmosis resulting in foetal death, or an infant living with many defects. Such a case would of course present little difficulty, and KELEMEN’s [1958] cases were presumably in this group. In the present experimental study no lesions were produced in the bulla or cochlea in guinea-pigs.","PeriodicalId":20405,"journal":{"name":"Practica oto-rhino-laryngologica","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000275019","citationCount":"6","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Practica oto-rhino-laryngologica","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000275019","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 6
Abstract
In conclusion, it may be said that congenital toxo-plasmosis as a cause of deafness is unlikely in man; it could not be said to be impossible. Acceptable criteria for such a diagnosis are difficult to see [Wright, 1971]. Low antibodies in the mother might be a factor in favour of transmission; high antibodies and evidence of infection during the relevant pregnancy would most likely lead to a classical case of congenital toxoplasmosis resulting in foetal death, or an infant living with many defects. Such a case would of course present little difficulty, and KELEMEN’s [1958] cases were presumably in this group. In the present experimental study no lesions were produced in the bulla or cochlea in guinea-pigs.