Colostral transfer of rinderpest neutralizing antibody to offspring of vaccinated dams.

K V Singh, O A Osman, I F el Cicy, T I Baz
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Abstract

The transfer of maternal antibodies to Friesian and buffalo calves born of dams vaccinated against rinderpest was through colostrum only. Colostral antibody titers at the time of parturition were higher than the serum titer. Two hours after suckling, a high level of rinderpest neutralizing antibodies was detected in the sera of newborn animals. The half-life of maternal antibodies in buffalo and Friesian calves was found to be approximately 33 and 29 days respectively. By the age of 7-8 months, 60 per cent of buffalo calves and 80 per cent of Friesian calves had no detectable levels of rinderpest neutralizing antibody.

牛瘟中和抗体向接种牛瘟疫苗的母鼠后代的初侧转移。
母源抗体仅通过初乳传递给接种牛瘟疫苗的母羊和水牛幼崽。分娩时初抗滴度高于血清滴度。在哺乳2小时后,新生动物血清中检测到高水平的牛瘟中和抗体。母源抗体在水牛和弗里西亚小牛体内的半衰期分别约为33天和29天。到7-8个月大的时候,60%的水牛和80%的弗里西亚小牛体内没有可检测到的牛瘟中和抗体。
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