M Drazniowsky, I S Parkinson, M K Ward, S M Channon, D N Kerr
{"title":"Raised serum nickel concentrations in chronic renal failure.","authors":"M Drazniowsky, I S Parkinson, M K Ward, S M Channon, D N Kerr","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>We have measured serum nickel concentrations using flameless atomic absorption spectrophotometry. In 71 normals the median concentration was 1.0 micrograms/L, range less than 0.6-3.0 micrograms/L. Increased concentrations (p less than 0.05) were found in patients with chronic renal failure (CRF) treated conservatively (median 1.6 micrograms/L, range less than 0.6-3.6 micrograms/L). Significantly increased concentrations (p less than 0.001) were found in patients treated by continuous ambulatory peritoneal dialysis (CAPD) (median 8.6 micrograms/L, range 5.4-11.4 micrograms/L) and haemodialysis. In patients on haemodialysis, post-dialysis concentrations (median 8.8 micrograms/L, range 3.0-21.4 micrograms/L) were significantly higher (p less than 0.001) than pre-dialysis values (median 8.6 micrograms/L, range 0.6-16.6 micrograms/L).</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"241-6"},"PeriodicalIF":0.0000,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
We have measured serum nickel concentrations using flameless atomic absorption spectrophotometry. In 71 normals the median concentration was 1.0 micrograms/L, range less than 0.6-3.0 micrograms/L. Increased concentrations (p less than 0.05) were found in patients with chronic renal failure (CRF) treated conservatively (median 1.6 micrograms/L, range less than 0.6-3.6 micrograms/L). Significantly increased concentrations (p less than 0.001) were found in patients treated by continuous ambulatory peritoneal dialysis (CAPD) (median 8.6 micrograms/L, range 5.4-11.4 micrograms/L) and haemodialysis. In patients on haemodialysis, post-dialysis concentrations (median 8.8 micrograms/L, range 3.0-21.4 micrograms/L) were significantly higher (p less than 0.001) than pre-dialysis values (median 8.6 micrograms/L, range 0.6-16.6 micrograms/L).
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