2 Trace element metabolism in the fetus and neonate

Patricia A. Pleban, Brenda S. Numerof, Frederick H. Wirth
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引用次数: 17

Abstract

The effects of trace metal nutrition on the fetus and neonate have been described. Since very little research has been done with the human fetus and neonate, much of our knowledge must be extrapolated from animal studies. In addition, most of the work centres around the effects of copper and zinc nutrition. Nutritional requirements (when known) for both enteral and total parenteral feeding of certain trace metals, as well as the bioavailability, have been discussed. Finally, methods of assessment of trace metal nutritional status have been discussed. These include direct measurement of metal concentrations and determination of biochemical indicators, such as metal-dependent enzyme activities—both of which are static indicators of nutritional status, and functional assessment of nutritional status which is a dynamic measure of trace metal nutrition and includes tests measuring the effects of metal nutrition on the function of cells, tissues, organs, and the host in general.

2胎儿和新生儿微量元素代谢
介绍了微量金属营养对胎儿和新生儿的影响。由于对人类胎儿和新生儿的研究很少,我们的大部分知识必须从动物研究中推断出来。此外,大多数工作都围绕着铜和锌营养的影响展开。已经讨论了某些微量金属的肠内和完全肠外喂养的营养需求(如果已知)以及生物利用度。最后讨论了微量金属营养状况的评价方法。这些包括金属浓度的直接测量和生化指标的测定,如金属依赖性酶活性,这两者都是营养状况的静态指标,以及营养状况的功能评估,这是微量金属营养的动态测量,包括测量金属营养对细胞、组织、器官和宿主功能的影响的测试。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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