Predictors of Age-Adjusted Pelvic Tilt Correction After Long-Segment Adult Spinal Deformity Correction.

IF 5.1 1区 医学 Q1 CLINICAL NEUROLOGY
Blake Holthaus, Nathan Ritchey, Joshua H Weinberg, Santino Cua, Eashwar Kantemneni, Kevin Agner, Luke Comisford, Heema Vyas, Yamenah Ambreen, Katelyn Sette, Witty Kwok, Abdul Karim Ghaith, Bryan Ladd, Siri Khalsa, David Xu, Stephanus Viljoen, Andrew Grossbach
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引用次数: 0

Abstract

Background context: Pelvic tilt (PT) reflects sagittal alignment compensation in adult spinal deformity and is associated with postoperative outcomes. Achievement of age-adjusted PT after long segment fusion demonstrates substantial improvements in health-related quality of life and a reduction of complications. However, many patients fail to normalize PT and predictors remain incompletely defined.

Purpose: This study aims to identify preoperative and surgical predictors of PT correction using age-adjusted thresholds in patients undergoing long-segment thoracolumbar fusion with pelvic fixation.

Study design: Retrospective cohort study.

Patient sample: Adult spinal deformity (ASD) patients undergoing long-segment thoracolumbar fusion with pelvic fixation with preoperative PT above age-adjusted targets (n=129).

Outcome measures: Primary outcome was achievement of age-adjusted PT at 12 months postoperative. Radiographic parameters included pelvic incidence (PI), pelvic tilt (PT), sacral slope (SS), lumbar lordosis (LL), T1 pelvic angle (T1PA), and proportional correction measures normalized to PI.

Methods: Patients were dichotomized based on PT normalization at 12 months. Extent of spinopelvic correction and deviation from ideal was calculated and normalized by PI. Mixed-effects multivariable logistic regression controlled for confounding variables. Univariate area under curve (AUC) assessed predictive performance.

Results: Patients who normalized PT at 12 months had lower baseline PI, PT, SS, and LL. When normalized to PI, these associations became stronger. T1PA deviation ratio, ΔLL/PI, and PI were identified as independent predictors of PT normalization. T1PA had the highest discriminatory ability (AUC=0.803), while PI was the strongest negative predictor (AUC=0.745).

Conclusion: PT correction depends on both baseline alignment and extent of surgical correction. Greater correction of LL and T1PA proportional to PI, were independently associated with PT normalization.

成人长节段脊柱畸形矫正后年龄调整骨盆倾斜矫正的预测因素。
背景:骨盆倾斜(PT)反映成人脊柱畸形的矢状面对齐补偿,并与术后结果相关。在长节段融合后实现年龄调整PT显示了健康相关生活质量的显著改善和并发症的减少。然而,许多患者未能使PT正常化,预测因素仍然不完全确定。目的:本研究旨在通过年龄调整阈值确定行长节段胸腰椎融合盆腔内固定术患者PT矫正的术前和手术预测因素。研究设计:回顾性队列研究。患者样本:成人脊柱畸形(ASD)患者接受长节段胸腰椎融合骨盆固定,术前PT高于年龄调整目标(n=129)。结果测量:主要结果是术后12个月年龄调整PT的实现。影像学参数包括骨盆发生率(PI)、骨盆倾斜(PT)、骶骨斜度(SS)、腰椎前凸(LL)、T1骨盆角(T1PA)以及归一化到PI的比例校正措施。方法:根据患者12个月的PT正常化对患者进行分类。计算脊柱骨盆矫正程度和偏离理想的程度,并通过PI归一化。混合效应多变量逻辑回归控制了混杂变量。单变量曲线下面积(AUC)评估预测性能。结果:在12个月恢复正常PT的患者具有较低的基线PI、PT、SS和LL。当标准化到PI时,这些关联变得更强。T1PA偏差比、ΔLL/PI和PI被确定为PT归一化的独立预测因子。T1PA具有最高的区分能力(AUC=0.803),而PI是最强的负向预测因子(AUC=0.745)。结论:PT矫正取决于基线对齐和手术矫正的程度。与PI成比例的LL和T1PA的较大校正与PT归一化独立相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Spine Journal
Spine Journal 医学-临床神经学
CiteScore
8.20
自引率
6.70%
发文量
680
审稿时长
13.1 weeks
期刊介绍: The Spine Journal, the official journal of the North American Spine Society, is an international and multidisciplinary journal that publishes original, peer-reviewed articles on research and treatment related to the spine and spine care, including basic science and clinical investigations. It is a condition of publication that manuscripts submitted to The Spine Journal have not been published, and will not be simultaneously submitted or published elsewhere. The Spine Journal also publishes major reviews of specific topics by acknowledged authorities, technical notes, teaching editorials, and other special features, Letters to the Editor-in-Chief are encouraged.
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