TurkRadLLM: A Compact MedGemma-Based Model for Structuring Turkish Lumbar and Cervical Spine MRI Reports-A Multi-reader Validation Study.

IF 3.1
Ahmet Harun Turgan, Hasan Çolakoğlu, Akif Demir, Zakir Sakcı
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Abstract

To develop and validate a compact, locally deployable MedGemma-based model converting unstructured Turkish spine MRI reports into structured six-field output. In this retrospective single-institution study, 5210 lumbar and 5017 cervical Turkish spine MRI reports were used to fine-tune MedGemma 4B IT with QLoRA. Silver-standard labels from a proprietary large language model served as training targets and as the reference for automated fidelity analyses, but not as the clinical reference standard. Evaluation comprised multi-reader validation of 180 authentic reports interleaved with 20 adversarial cases, a second round in which the readers scored the silver labels themselves, and comparison on the full held-out set against a rule-based baseline, the non-fine-tuned base model, and a much larger model. Every output was valid, schema-conformant JSON, and the grouped acceptance rate was 100% (95% CI 97.9-100), though one reader judged negative-finding lists incomplete in 57.8% of reports. On the full held-out set (1025 reports), fine-tuning increased agreement with the silver-label impression from 17.7% to 67.1% and urgent-flag sensitivity against the silver reference from 18.8% to 62.5% (both p < .001); the larger non-fine-tuned model reached 27.5% and 50.0%, and a rule-based baseline 99.0% on body region. When the readers scored the silver labels themselves, the model was rated higher on negative findings and lower on the impression. Deployment required 14.75 GB of GPU memory on a consumer card. Fine-tuning a compact medical language model produced structured output rated acceptable by clinicians, though negative-finding completeness remained reader-dependent. The gain lay in content-level fidelity rather than output validity.

TurkRadLLM:一种基于medgemma的紧凑模型,用于构建土耳其腰椎和颈椎MRI报告-一项多阅读器验证研究。
开发并验证一种紧凑的、本地可部署的medgemma模型,将非结构化的土耳其脊柱MRI报告转换为结构化的六场输出。在这项回顾性单机构研究中,5210例腰椎和5017例颈椎土耳其脊柱MRI报告被用于微调MedGemma 4B IT与QLoRA。来自专有大型语言模型的银标准标签作为训练目标和自动保真度分析的参考,但不作为临床参考标准。评估包括对180份真实报告的多读者验证,其中交织着20个对抗案例,第二轮中读者自己给银标签打分,并将完整的设定与基于规则的基线、非微调的基础模型和更大的模型进行比较。每个输出都是有效的,符合模式的JSON,分组接受率为100% (95% CI 97.9-100),尽管一位读者在57.8%的报告中判断负面发现列表不完整。在全套(1025份报告)中,微调将银色标签印象的一致性从17.7%提高到67.1%,将紧急标志对银色参考的敏感性从18.8%提高到62.5%
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