{"title":"Evaluating prompting strategies and large language models in systematic literature review screening: Relevance and task-stage classification.","authors":"Binglan Han, Anuradha Mathrani, Vajisha Udayangi Wanniarachchi, Teo Susnjak","doi":"10.1017/rsm.2026.10110","DOIUrl":null,"url":null,"abstract":"<p><p>This study quantifies how prompting strategies interact with large language models (LLMs) to automate the screening stage of systematic literature reviews (SLRs). We evaluate six LLMs (GPT-4o, GPT-4o-mini, DeepSeek-Chat-V3, Gemini-2.5-Flash, Claude-3.5-Haiku, and Llama-4-Maverick) under five prompt types (zero-shot, few-shot, chain-of-thought [CoT], CoT-few-shot, and self-reflection) across relevance classification and six Level-2 tasks, using accuracy, precision, recall, and F1. Results show pronounced model-prompt interaction effects within this SLR-automation corpus: zero-shot maximizes recall for high-sensitivity relevance screening; CoT-few-shot yields stronger precision and F1; and self-reflection underperforms due to over-inclusivity and instability across models. GPT-4o and DeepSeek provide robust overall performance, while GPT-4o-mini performs competitively at a substantially lower dollar cost. A cost-performance analysis for relevance classification (per 1,000 abstracts) reveals large absolute differences among model-prompt pairings; GPT-4o-Mini remains low-cost across prompts, and structured prompts (CoT/CoT-few-shot) on GPT-4o-Mini offer attractive F1 at a small incremental cost. The cost-performance analysis also suggests that future screening workflows could incorporate staged, cost-aware procedures: (1) using lower-cost, high-recall configurations for initial screening and (2) reserving higher-cost or more precision-oriented configurations for later triage or uncertain records. These findings highlight LLMs' uneven but promising potential to support screening within corpora similar to the SLR-automation corpus examined in this study. Further validation is needed before generalising these results to broader systematic review screening tasks. By systematically analyzing prompt-model interactions, we provide a comparative benchmark and practical guidance for task-adaptive LLM deployment.</p>","PeriodicalId":226,"journal":{"name":"Research Synthesis Methods","volume":" ","pages":"1-40"},"PeriodicalIF":8.0000,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research Synthesis Methods","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1017/rsm.2026.10110","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATHEMATICAL & COMPUTATIONAL BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
This study quantifies how prompting strategies interact with large language models (LLMs) to automate the screening stage of systematic literature reviews (SLRs). We evaluate six LLMs (GPT-4o, GPT-4o-mini, DeepSeek-Chat-V3, Gemini-2.5-Flash, Claude-3.5-Haiku, and Llama-4-Maverick) under five prompt types (zero-shot, few-shot, chain-of-thought [CoT], CoT-few-shot, and self-reflection) across relevance classification and six Level-2 tasks, using accuracy, precision, recall, and F1. Results show pronounced model-prompt interaction effects within this SLR-automation corpus: zero-shot maximizes recall for high-sensitivity relevance screening; CoT-few-shot yields stronger precision and F1; and self-reflection underperforms due to over-inclusivity and instability across models. GPT-4o and DeepSeek provide robust overall performance, while GPT-4o-mini performs competitively at a substantially lower dollar cost. A cost-performance analysis for relevance classification (per 1,000 abstracts) reveals large absolute differences among model-prompt pairings; GPT-4o-Mini remains low-cost across prompts, and structured prompts (CoT/CoT-few-shot) on GPT-4o-Mini offer attractive F1 at a small incremental cost. The cost-performance analysis also suggests that future screening workflows could incorporate staged, cost-aware procedures: (1) using lower-cost, high-recall configurations for initial screening and (2) reserving higher-cost or more precision-oriented configurations for later triage or uncertain records. These findings highlight LLMs' uneven but promising potential to support screening within corpora similar to the SLR-automation corpus examined in this study. Further validation is needed before generalising these results to broader systematic review screening tasks. By systematically analyzing prompt-model interactions, we provide a comparative benchmark and practical guidance for task-adaptive LLM deployment.
期刊介绍:
Research Synthesis Methods is a reputable, peer-reviewed journal that focuses on the development and dissemination of methods for conducting systematic research synthesis. Our aim is to advance the knowledge and application of research synthesis methods across various disciplines.
Our journal provides a platform for the exchange of ideas and knowledge related to designing, conducting, analyzing, interpreting, reporting, and applying research synthesis. While research synthesis is commonly practiced in the health and social sciences, our journal also welcomes contributions from other fields to enrich the methodologies employed in research synthesis across scientific disciplines.
By bridging different disciplines, we aim to foster collaboration and cross-fertilization of ideas, ultimately enhancing the quality and effectiveness of research synthesis methods. Whether you are a researcher, practitioner, or stakeholder involved in research synthesis, our journal strives to offer valuable insights and practical guidance for your work.