Body mass index is associated with muscle strength, functional capacity, balance, and quality of life in patients with type 2 diabetes: A cross-sectional study.

IF 1.6 4区医学 Q2 REHABILITATION

Physiotherapy Theory and Practice Pub Date : 2026-10-16 DOI:10.1080/09593985.2026.2745704

Sule Topcu Sahin, Semiramis Ozyilmaz, Muhammed Tunc

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引用次数: 0

Abstract

Background: Type 2 diabetes mellitus (T2DM) is accompanied by obesity and elevated body mass index (BMI), which may be associated with poorer physical function and quality of life (QOL). However, associations of BMI with muscle strength, functional capacity, balance, and QOL have not been comprehensively evaluated together in T2DM.

Purpose: To evaluate associations of BMI with muscle strength, functional capacity, balance, and QOL in patients with T2DM.

Methods: Patient characteristics were recorded. Body composition, muscle strength, functional capacity, balance, and QOL were assessed using validated measures. Bivariate Pearson correlations were supplemented by partial correlations controlling for age, sex, height, diabetes duration, glycated hemoglobin A1c (HbA1c), and insulin use.

Results: Fifty patients with T2DM were included (age: 52.90 ± 9.27 years; BMI: 33.76 ± 7.18 kg/m²). In unadjusted analyses, higher BMI was associated with greater adiposity, lower skeletal muscle mass percentage and handgrip strength, shorter 6-minute walk test (6MWT) distance, lower Berg Balance Scale scores, and poorer QOL, but not with quadriceps strength, resting metabolic rate, Biodex balance parameters, or several QOL subdomains. After adjustment, BMI remained associated with body fat percentage (partial r = 0.854, p < .001), skeletal muscle mass percentage (partial r = -0.665, p < .001), 6MWT distance (partial r = -0.545, p < .001), and Nottingham Health Profile (NHP) pain (partial r = 0.426, p = .004), mobility (partial r = 0.440, p = .003), and total score (partial r = 0.351, p = .019). Associations with handgrip strength (p = .728) and Berg Balance test score were no longer significant (p = .069).

Conclusion: After adjustment for confounders, higher BMI remained associated with higher body fat percentage, lower skeletal muscle mass percentage, shorter 6MWT distance, and poorer QOL, whereas associations with handgrip strength and functional balance were attenuated. BMI-related functional findings should be interpreted cautiously in light of potential confounding.

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体重指数与2型糖尿病患者的肌肉力量、功能能力、平衡和生活质量相关：一项横断面研究

背景：2型糖尿病（T2DM）伴有肥胖和身体质量指数（BMI）升高，这可能与身体功能和生活质量（QOL）下降有关。然而，在T2DM中，BMI与肌力、功能能力、平衡和生活质量的关系尚未被综合评估。目的：评价BMI与T2DM患者肌肉力量、功能能力、平衡和生活质量的关系。方法：记录患者特征。采用有效的测量方法评估身体成分、肌肉力量、功能能力、平衡和生活质量。双变量Pearson相关性补充了控制年龄、性别、身高、糖尿病病程、糖化血红蛋白A1c （HbA1c）和胰岛素使用的偏相关性。结果：纳入T2DM患者50例（年龄：52.90±9.27岁；BMI: 33.76±7.18 kg/m2）。在未经调整的分析中，较高的BMI与较高的肥胖、较低的骨骼肌质量百分比和握力、较短的6分钟步行测试（6MWT）距离、较低的Berg平衡量表评分和较差的生活质量相关，但与股四头肌强度、静息代谢率、Biodex平衡参数或几个生活质量子域无关。调整后，BMI与体脂率仍然存在相关性(部分r = 0.854, p r = -0.665, p r = -0.545, p r = 0.426, p =。004)，迁移率(部分r = 0.440, p =。003)，总分（部分r = 0.351, p = 0.019）。与握力（p = .728）和Berg Balance测试分数的相关性不再显著（p = .069）。结论：在调整混杂因素后，较高的BMI仍然与较高的体脂率、较低的骨骼肌质量百分比、较短的6MWT距离和较差的生活质量相关，而与握力和功能平衡的相关性减弱。bmi相关的功能检查结果应根据潜在的混淆因素谨慎解释。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Physiotherapy Theory and Practice REHABILITATION-

CiteScore

3.40

自引率

10.00%

发文量

300

期刊介绍： The aim of Physiotherapy Theory and Practice is to provide an international, peer-reviewed forum for the publication, dissemination, and discussion of recent developments and current research in physiotherapy/physical therapy. The journal accepts original quantitative and qualitative research reports, theoretical papers, systematic literature reviews, clinical case reports, and technical clinical notes. Physiotherapy Theory and Practice; promotes post-basic education through reports, reviews, and updates on all aspects of physiotherapy and specialties relating to clinical physiotherapy.