Guido C. Hilgers, Simon J. Woodings, Thomas A. Foppen, Jochem W.H. Wolthaus, André W. Minken, Bas W. Raaymakers, Bram van Asselen
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引用次数: 0
Abstract
Background and Purpose
Magnetic resonance-guided radiotherapy systems require comprehensive quality assurance (QA) programs to ensure safe and precise treatment delivery. This study evaluates the long-term behavior and variability of linac-related QA results across three clinically operated 1.5 T MRI-linacs at a single institution and assesses compliance with tolerance limits.
Materials and Methods
QA data acquired over a six-year period from three clinically operated 1.5 T MRI-linacs were retrospectively analyzed. A range of linac-related dosimetric and mechanical QA tests was included. Performance envelopes (mean ± 2 SD) were constructed to characterize variability relative to tolerance limits.
Results
For 11 of 13 QA tests, performance envelopes for the associated metrics remained within the applied tolerance limits. For the two remaining tests, envelopes slightly extended beyond these limits. These deviations were not considered clinically relevant, and their underlying causes were understood. No progressive trends of clinical relevance were observed in the linac-specific time series.
Conclusions
Stability of linac-related QA results was demonstrated over six years across three MRI-linacs, supporting reconsideration of the QA program.
背景与目的磁共振引导放射治疗系统需要全面的质量保证(QA)程序,以确保安全和精确的治疗递送。本研究评估了同一机构三个临床操作的1.5 T mri直线相关QA结果的长期行为和可变性,并评估了耐受极限的依从性。材料和方法回顾性分析3例临床手术的1.5 T mri直线患者6年的sqa数据。包括一系列与直线相关的剂量学和机械QA测试。构建性能包络(mean±2 SD)来表征相对于公差极限的可变性。结果对于13个QA测试中的11个,相关指标的性能信封保持在应用的公差范围内。对于剩下的两个测试,封套稍微超出了这些限制。这些偏差被认为与临床无关,其根本原因也已被了解。在linac特异性时间序列中未观察到临床相关性的进展趋势。结论:在3个mri直线机中,与直线相关的QA结果的稳定性在6年的时间里得到了证明,支持了对QA计划的重新考虑。