A 0/2-Hour Algorithm Using a Novel Point-of-Care High-Sensitivity Cardiac Troponin I Assay for Suspected Myocardial Infarction.

IF 3.4 2区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

American heart journal Pub Date : 2026-10-13 DOI:10.1016/j.ahj.2026.107625

Luca Koechlin, Pedro Lopez-Ayala, Jasper Boeddinghaus, Nina Sigg, Koray Durak, Thomas Nestelberger, Karin Wildi, Ivo Strebel, Paolo Bima, Luca Crisanti, Lourdes Herraiz Recuenco, Alperen Yueksel, Òscar Miró, F Javier Martin-Sanchez, Damian Kawecki, Dagmar I Keller, Michael Christ, Andreas Buser, Héctor Rodriguez Cetina Biefer, Omer Dzemali, Marianne Nordlund Broughton, Felix Mahfoud, Christian Mueller

引用次数: 0

Abstract

This letter describes the derivation and internal validation of an assay-specific hs-cTnI-SPINCHIP 0/2h-algorithm for rapid triage of patients with suspected myocardial infarction (MI) in the emergency department (ED). The algorithm provided very high safety for rule-out, high accuracy for rule-in, and enabled definitive triage within 2 hours in approximately 80% of patients. These findings support the clinical potential of the novel point-of-care hs-cTnI-SPINCHIP assay for accelerated ED decision-making.

查看原文本刊更多论文

一种新型的即时高灵敏度心肌肌钙蛋白I检测疑似心肌梗死的0/2小时算法

这封信描述了一种测定特异性hs-cTnI-SPINCHIP 0/2h算法的推导和内部验证，该算法用于急诊科（ED）疑似心肌梗死（MI）患者的快速分类。该算法提供了非常高的排除安全性，规则输入的准确性很高，并且在大约80%的患者中实现了2小时内的最终分诊。这些发现支持了新型的即时his - ctni - spinchip检测加速ED决策的临床潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

American heart journal 医学-心血管系统

CiteScore

8.20

自引率

2.10%

发文量

214

审稿时长

38 days

期刊介绍： The American Heart Journal will consider for publication suitable articles on topics pertaining to the broad discipline of cardiovascular disease. Our goal is to provide the reader primary investigation, scholarly review, and opinion concerning the practice of cardiovascular medicine. We especially encourage submission of 3 types of reports that are not frequently seen in cardiovascular journals: negative clinical studies, reports on study designs, and studies involving the organization of medical care. The Journal does not accept individual case reports or original articles involving bench laboratory or animal research.