{"title":"Shedding light on the efficacy of psychodynamic treatment targeting depression for patients with comorbid narcissistic personality disorder.","authors":"Maisan Mansour, Yogev Kivity, Sigal Zilcha-Mano","doi":"10.1080/10503307.2026.2738631","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Major depressive disorder (MDD) frequently co-occurs with narcissistic personality disorder (NPD). Despite the clinical relevance of this comorbidity, little is known about the efficacy of short-term depression-focused treatments for individuals with comorbid NPD. This study examines whether individuals with comorbid MDD and NPD benefit from treatment and whether NPD diagnostic status changes during therapy.</p><p><strong>Method: </strong>One hundred patients in a randomized controlled trial (RCT) were assessed for NPD (<i>n </i>= 14) using the Structured Interview for DSM-IV. Participants were randomly assigned to supportive therapy or supportive-expressive therapy. Depression severity was measured throughout therapy by the Hamilton Rating Scale for Depression (HRSD). Multilevel models were used to assess treatment efficacy and changes in NPD prevalence.</p><p><strong>Results: </strong>Patients with comorbid MDD and NPD demonstrated significantly greater depressive symptom reduction than those without NPD. However, no significant changes were found in NPD diagnosis status across therapy.</p><p><strong>Conclusion: </strong>These findings challenge the assumptions that NPD is a negative prognostic factor for depression treatment. Rather, they suggest that short-term psychodynamic interventions may effectively reduce depressive symptoms for patients with comorbid NPD, highlighting the need for further research into treatment mechanisms and patient subtypes.</p>","PeriodicalId":48159,"journal":{"name":"Psychotherapy Research","volume":" ","pages":"1-11"},"PeriodicalIF":3.8000,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Psychotherapy Research","FirstCategoryId":"102","ListUrlMain":"https://doi.org/10.1080/10503307.2026.2738631","RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PSYCHOLOGY, CLINICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: Major depressive disorder (MDD) frequently co-occurs with narcissistic personality disorder (NPD). Despite the clinical relevance of this comorbidity, little is known about the efficacy of short-term depression-focused treatments for individuals with comorbid NPD. This study examines whether individuals with comorbid MDD and NPD benefit from treatment and whether NPD diagnostic status changes during therapy.
Method: One hundred patients in a randomized controlled trial (RCT) were assessed for NPD (n = 14) using the Structured Interview for DSM-IV. Participants were randomly assigned to supportive therapy or supportive-expressive therapy. Depression severity was measured throughout therapy by the Hamilton Rating Scale for Depression (HRSD). Multilevel models were used to assess treatment efficacy and changes in NPD prevalence.
Results: Patients with comorbid MDD and NPD demonstrated significantly greater depressive symptom reduction than those without NPD. However, no significant changes were found in NPD diagnosis status across therapy.
Conclusion: These findings challenge the assumptions that NPD is a negative prognostic factor for depression treatment. Rather, they suggest that short-term psychodynamic interventions may effectively reduce depressive symptoms for patients with comorbid NPD, highlighting the need for further research into treatment mechanisms and patient subtypes.
期刊介绍:
Psychotherapy Research seeks to enhance the development, scientific quality, and social relevance of psychotherapy research and to foster the use of research findings in practice, education, and policy formulation. The Journal publishes reports of original research on all aspects of psychotherapy, including its outcomes, its processes, education of practitioners, and delivery of services. It also publishes methodological, theoretical, and review articles of direct relevance to psychotherapy research. The Journal is addressed to an international, interdisciplinary audience and welcomes submissions dealing with diverse theoretical orientations, treatment modalities.