An epigenetic program dictates MYC amplification dynamics that promote transient, extrachromosomal, and inherited genomic events

IF 16 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Molecular Cell Pub Date : 2026-10-01 DOI:10.1016/j.molcel.2026.09.032

Benjamin I. Ferman,Chloe Azadegan,John Santoro,Anushka Udara,Madison A. Lineberger,William Lautert-Dutra,Ethan Sumner,Logan McCullough,Erin O’Donnell,Kashish Chetal,Jade Wilson,Zach Gray,Manna Ahmed,Zhijie Deng,Yan Xiong,H. Umit Kaniskan,Damayanti Chakraborty,Thomas L. Clarke,Sedona E. Murphy,Martin Walsh,Alfonso Bellacosa,Hayan Lee,Jian Jin,Capucine Van Rechem,Michael S. Lawrence,Ruslan I. Sadreyev,Johnathan R. Whetstine

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表观遗传程序决定MYC扩增动力学，促进瞬时，染色体外和遗传基因组事件

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Molecular Cell 生物-生化与分子生物学

CiteScore

26.00

自引率

3.80%

发文量

389

审稿时长

1 months

期刊介绍： Molecular Cell is a companion to Cell, the leading journal of biology and the highest-impact journal in the world. Launched in December 1997 and published monthly. Molecular Cell is dedicated to publishing cutting-edge research in molecular biology, focusing on fundamental cellular processes. The journal encompasses a wide range of topics, including DNA replication, recombination, and repair; Chromatin biology and genome organization; Transcription; RNA processing and decay; Non-coding RNA function; Translation; Protein folding, modification, and quality control; Signal transduction pathways; Cell cycle and checkpoints; Cell death; Autophagy; Metabolism.