Biologic and Synthetic Augmentation in Rotator Cuff Repair

Peter Boufadel,Mohammad Daher,James R. Satalich,Favian Su,Adam Lindsay,Adam Z. Khan,Eric M. Black,Joseph A. Abboud,Hafiz F. Kassam
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Abstract

➢ Biologic and synthetic augmentation grafts have been developed to enhance both the mechanical integrity of rotator cuff repairs and the biologic healing at the tendon-bone interface, particularly in the setting of compromised tissue quality. ➢ Xenograft augmentation is no longer favored because of inconsistent clinical outcomes, inflammatory responses, and a lack of supportive high-quality evidence. ➢ Allograft and synthetic graft augmentation may provide benefit in selected cases; however, optimal indications, implant selection, and long-term outcomes remain incompletely defined. ➢ Bioinductive collagen implants currently demonstrate the highest level of clinical evidence, with Level-I studies supporting improved structural healing and reduced retear rates in appropriately selected patients. ➢ The long head of the biceps tendon autograft represents a viable, cost-effective biologic augmentation option when available, providing favorable biologic compatibility and surgical versatility.
肩袖修复中的生物和合成增强
目前已开发出生物和合成增强移植物,以增强肩袖修复的机械完整性和肌腱-骨界面的生物愈合,特别是在组织质量受损的情况下。由于不一致的临床结果、炎症反应和缺乏支持性的高质量证据,异种移植物增强术不再受到青睐。(五)同种异体移植物和合成移植物增强术可在特定病例中提供益处;然而,最佳适应症、种植体选择和长期结果仍不完全确定。生物诱导胶原植入物目前具有最高水平的临床证据,一级研究支持在适当选择的患者中改善结构愈合并降低复发率。自体二头肌肌腱长头在可行的情况下是一种可行的、具有成本效益的生物增强选择,具有良好的生物相容性和手术多功能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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