{"title":"Scrambler Therapy for Neuropathic Pain After Spinal Cord Injury: Two Case Reports.","authors":"Zhu Wang, Philippines Cabahug, Thomas J Smith","doi":"10.46292/sci25-00143","DOIUrl":null,"url":null,"abstract":"<p><p>Neuropathic pain after spinal cord injury (SCI) is common and often refractory to treatment. Scrambler Therapy (ST) is a noninvasive neuromodulation approach that delivers synthetic \"nonpain\" signals via cutaneous electrodes. We report 2 cases of SCI-related neuropathic pain treated with ST. One patient experienced transient and inconsistent relief, while the other achieved substantial, durable improvement with functional recovery and complete response after retreatment. ST was well tolerated with minimal adverse effects. These cases highlight variable response and support further study of ST as a potential treatment for refractory SCI-related neuropathic pain.</p>","PeriodicalId":46769,"journal":{"name":"Topics in Spinal Cord Injury Rehabilitation","volume":"32 4","pages":"137-140"},"PeriodicalIF":1.4000,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13621287/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Topics in Spinal Cord Injury Rehabilitation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46292/sci25-00143","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/9/28 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"REHABILITATION","Score":null,"Total":0}
引用次数: 0
Abstract
Neuropathic pain after spinal cord injury (SCI) is common and often refractory to treatment. Scrambler Therapy (ST) is a noninvasive neuromodulation approach that delivers synthetic "nonpain" signals via cutaneous electrodes. We report 2 cases of SCI-related neuropathic pain treated with ST. One patient experienced transient and inconsistent relief, while the other achieved substantial, durable improvement with functional recovery and complete response after retreatment. ST was well tolerated with minimal adverse effects. These cases highlight variable response and support further study of ST as a potential treatment for refractory SCI-related neuropathic pain.
期刊介绍:
Now in our 22nd year as the leading interdisciplinary journal of SCI rehabilitation techniques and care. TSCIR is peer-reviewed, practical, and features one key topic per issue. Published topics include: mobility, sexuality, genitourinary, functional assessment, skin care, psychosocial, high tetraplegia, physical activity, pediatric, FES, sci/tbi, electronic medicine, orthotics, secondary conditions, research, aging, legal issues, women & sci, pain, environmental effects, life care planning