Lung microenvironment proteomics identifies immune protein expression in interstitial pneumonia with autoimmune features.

IF 4.4 3区医学 Q1 RESPIRATORY SYSTEM

ERJ Open Research Pub Date : 2026-09-28 eCollection Date: 2026-09-01 DOI:10.1183/23120541.00328-2026

Linh T Ngo, Erik Way, Caroline Muegge, Ariel Barnhardt, Michaella J Rekowski, Bryant R England, Paul J Wolters, Philip L Molyneaux, Joyce S Lee, Joshua J Solomon, Koji Kuronuma, Michael P Washburn, Scott M Matson

引用次数: 0

Abstract

This study characterised differential protein expression using label-free proteomics of the lung microenvironment using bronchoalveolar lavage fluid and identified increased immune protein expression in the IPAF lung compared to IPF https://bit.ly/4edhp3B.

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肺微环境蛋白质组学鉴定具有自身免疫性特征的间质性肺炎的免疫蛋白表达。

本研究利用支气管肺泡灌洗液对肺微环境进行无标记蛋白质组学分析，表征了差异蛋白表达，并发现与IPF相比，IPAF肺中免疫蛋白表达增加https://bit.ly/4edhp3B。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ERJ Open Research Medicine-Pulmonary and Respiratory Medicine

CiteScore

6.20

自引率

4.30%

发文量

273

审稿时长

8 weeks

期刊介绍： ERJ Open Research is a fully open access original research journal, published online by the European Respiratory Society. The journal aims to publish high-quality work in all fields of respiratory science and medicine, covering basic science, clinical translational science and clinical medicine. The journal was created to help fulfil the ERS objective to disseminate scientific and educational material to its members and to the medical community, but also to provide researchers with an affordable open access specialty journal in which to publish their work.