{"title":"Uncertainty-guided decoupled complementary network for binary semi-supervised medical image segmentation.","authors":"Dongsheng Wang, Xiaohan Lang","doi":"10.1088/2057-1976/aea90e","DOIUrl":null,"url":null,"abstract":"<p><p>Semi-supervised medical image segmentation methods have drawn wide attention as they reduce reliance on heavily annotated data. However, existing models suffer from confirmation bias with limited annotations, and structural or parameter coupling hinders self-correction, especially for medical images with ambiguous boundaries, low contrast and complex backgrounds. To address these issues, we propose an uncertainty-guided decoupling and complementary network (UGDC-Net) for binary medical image segmentation. It uses a contrastive mechanism to filter high-uncertainty regions of sub-networks for avoiding model collapse, and a dynamic competition mechanism to tackle the weight coupling bottleneck in teacher-student frameworks. Reliable pseudo-labels from high-performance sub-networks and supplementary ones from inconsistent high-uncertainty regions are integrated to provide diverse supervision, enhancing the model's exploration of small targets. Experiments on left atrium, Pancreas-CT and ISIC datasets validate that UGDC-Net outperforms state-of-the-art methods on binary segmentation tasks.</p>","PeriodicalId":8896,"journal":{"name":"Biomedical Physics & Engineering Express","volume":"12 5","pages":""},"PeriodicalIF":2.0000,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical Physics & Engineering Express","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1088/2057-1976/aea90e","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
Semi-supervised medical image segmentation methods have drawn wide attention as they reduce reliance on heavily annotated data. However, existing models suffer from confirmation bias with limited annotations, and structural or parameter coupling hinders self-correction, especially for medical images with ambiguous boundaries, low contrast and complex backgrounds. To address these issues, we propose an uncertainty-guided decoupling and complementary network (UGDC-Net) for binary medical image segmentation. It uses a contrastive mechanism to filter high-uncertainty regions of sub-networks for avoiding model collapse, and a dynamic competition mechanism to tackle the weight coupling bottleneck in teacher-student frameworks. Reliable pseudo-labels from high-performance sub-networks and supplementary ones from inconsistent high-uncertainty regions are integrated to provide diverse supervision, enhancing the model's exploration of small targets. Experiments on left atrium, Pancreas-CT and ISIC datasets validate that UGDC-Net outperforms state-of-the-art methods on binary segmentation tasks.
期刊介绍:
BPEX is an inclusive, international, multidisciplinary journal devoted to publishing new research on any application of physics and/or engineering in medicine and/or biology. Characterized by a broad geographical coverage and a fast-track peer-review process, relevant topics include all aspects of biophysics, medical physics and biomedical engineering. Papers that are almost entirely clinical or biological in their focus are not suitable. The journal has an emphasis on publishing interdisciplinary work and bringing research fields together, encompassing experimental, theoretical and computational work.