{"title":"The art and science of deprescribing: A practical guide for nurse practitioners.","authors":"Jennifer Lynn Tuttle","doi":"10.1097/JXX.0000000000001359","DOIUrl":null,"url":null,"abstract":"<p><strong>Abstract: </strong>Inappropriate polypharmacy is a critical threat to patient safety, contributing to adverse drug events, falls, and diminished quality of life. Although an essential clinical intervention, deprescribing remains underused due to clinician-specific and systemic barriers. This article explores deprescribing as both an art and a science, providing a structured five-step clinical framework tailored for nurse practitioners. Two case scenarios, involving a 50-year-old woman transitioning to hospice and a 74-year-old man in primary care, illustrate how to implement comprehensive medication reviews, use tools like the Beers Criteria, realign therapeutic goals, and safely substitute high-risk agents. By synthesizing pharmacological science with shared decision making, nurse practitioners can successfully mitigate patient anxiety, overcome resource barriers, and normalize deprescribing as a standard of holistic, patient-centered care.</p>","PeriodicalId":17179,"journal":{"name":"Journal of the American Association of Nurse Practitioners","volume":" ","pages":""},"PeriodicalIF":1.6000,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the American Association of Nurse Practitioners","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/JXX.0000000000001359","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract: Inappropriate polypharmacy is a critical threat to patient safety, contributing to adverse drug events, falls, and diminished quality of life. Although an essential clinical intervention, deprescribing remains underused due to clinician-specific and systemic barriers. This article explores deprescribing as both an art and a science, providing a structured five-step clinical framework tailored for nurse practitioners. Two case scenarios, involving a 50-year-old woman transitioning to hospice and a 74-year-old man in primary care, illustrate how to implement comprehensive medication reviews, use tools like the Beers Criteria, realign therapeutic goals, and safely substitute high-risk agents. By synthesizing pharmacological science with shared decision making, nurse practitioners can successfully mitigate patient anxiety, overcome resource barriers, and normalize deprescribing as a standard of holistic, patient-centered care.
期刊介绍：
The Journal of the American Association of Nurse Practitioners (JAANP) is a monthly peer-reviewed professional journal that serves as the official publication of the American Association of Nurse Practitioners.
Published since 1989, the JAANP provides a strong clinical focus with articles related to primary, secondary, and tertiary care, nurse practitioner education, health policy, ethics and ethical issues, and health care delivery. The journal publishes original research, integrative/comprehensive reviews, case studies, a variety of topics in clinical practice, and theory-based articles related to patient and professional education. Although the majority of nurse practitioners function in primary care, there is an increasing focus on the provision of care across all types of systems from acute to long-term care settings.
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