SenTrack: A Live-Cell, Single-Cell Imaging and Machine-Learning Approach to Quantify Lysosomal Remodeling as a Redox-Linked Marker of Senescence in IMR-90 Fibroblasts

IF 8 2区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI:10.1016/j.freeradbiomed.2026.08.058

Javier Estrada Toro, J. Andrés Meléndez

引用次数: 0

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SenTrack：一种活细胞、单细胞成像和机器学习方法来量化溶酶体重塑作为IMR-90成纤维细胞氧化还原酶相关衰老标志物

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来源期刊

Free Radical Biology and Medicine 医学-内分泌学与代谢

CiteScore

14.00

自引率

4.10%

发文量

850

审稿时长

22 days

期刊介绍： Free Radical Biology and Medicine is a leading journal in the field of redox biology, which is the study of the role of reactive oxygen species (ROS) and other oxidizing agents in biological systems. The journal serves as a premier forum for publishing innovative and groundbreaking research that explores the redox biology of health and disease, covering a wide range of topics and disciplines. Free Radical Biology and Medicine also commissions Special Issues that highlight recent advances in both basic and clinical research, with a particular emphasis on the mechanisms underlying altered metabolism and redox signaling. These Special Issues aim to provide a focused platform for the latest research in the field, fostering collaboration and knowledge exchange among researchers and clinicians.