Outcomes, Quality of Life, and Value in Cervical Spine Oncology: Neurological Recovery, Patient-Reported Outcomes, and Prognostic Decision-Making.

IF 1.9 4区医学 Q3 CLINICAL NEUROLOGY

Clinical Spine Surgery Pub Date : 2026-09-21 DOI:10.1097/BSD.0000000000002167

Tyler M Compton, Theodore A Joaquin, Mark A Plantz, Jason D Tegethoff, Srikanth N Divi

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引用次数: 0

Abstract

Study design: Narrative review.

Objective: To provide an overview of outcomes, cost-effectiveness, local control, survivorship, and prognostic decision-making in cervical spine oncology.

Summary of background data: Cervical spine oncology includes both metastatic and primary tumors, each with distinct treatment goals and oncologic considerations. Cervical spine tumors can impair quality of life through pain, neurological deficits, and mechanical instability.

Methods: This review synthesizes current literature on neurological and functional outcomes, health-related quality of life (HRQOL), cost-effectiveness, local control, survivorship, and prognostic decision-making in cervical spine oncology.

Results: Prospective multicenter studies demonstrate significant improvements in pain, neurological function, and HRQOL after surgery for metastatic cervical spine disease. Separation surgery followed by stereotactic body radiotherapy (SBRT) achieves high rates of local control in appropriately selected patients. Cost-effectiveness is greatest among patients with acute neurological compromise and favorable survival prognoses. We additionally review prognostic classification systems, machine-learning algorithms, and outcomes in primary cervical spine tumors including cervical chordoma.

Conclusions: Cervical spine oncology requires individualized multidisciplinary treatment. Prospective outcomes data, validated patient-reported outcome instruments, modern radiation strategies, and prognostic algorithms support contemporary decision-making in patients with cervical spine tumors.

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颈椎肿瘤的预后、生活质量和价值：神经恢复、患者报告的预后和预后决策。

研究设计：叙述性回顾。目的：综述颈椎肿瘤的预后、成本效益、局部控制、生存率和预后决策。背景资料总结：颈椎肿瘤包括转移性肿瘤和原发肿瘤，每一种肿瘤都有不同的治疗目标和肿瘤学考虑。颈椎肿瘤可通过疼痛、神经功能缺损和机械不稳定影响生活质量。方法：本综述综合了目前有关颈椎肿瘤患者的神经和功能结局、健康相关生活质量（HRQOL）、成本-效果、局部控制、生存率和预后决策的文献。结果：前瞻性多中心研究表明转移性颈椎疾病手术后疼痛、神经功能和HRQOL有显著改善。在适当选择的患者中，分离手术后的立体定向放射治疗（SBRT）达到了很高的局部控制率。成本效益在急性神经损害和良好生存预后的患者中是最大的。我们还回顾了包括颈脊索瘤在内的原发性颈椎肿瘤的预后分类系统、机器学习算法和预后。结论：颈椎肿瘤需要个体化多学科治疗。前瞻性结果数据、经过验证的患者报告结果工具、现代放射策略和预后算法支持颈椎肿瘤患者的当代决策。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Spine Surgery Medicine-Surgery

CiteScore

3.00

自引率

5.30%

发文量

236

期刊介绍： Clinical Spine Surgery is the ideal journal for the busy practicing spine surgeon or trainee, as it is the only journal necessary to keep up to date with new clinical research and surgical techniques. Readers get to watch leaders in the field debate controversial topics in a new controversies section, and gain access to evidence-based reviews of important pathologies in the systematic reviews section. The journal features a surgical technique complete with a video, and a tips and tricks section that allows surgeons to review the important steps prior to a complex procedure. Clinical Spine Surgery provides readers with primary research studies, specifically level 1, 2 and 3 studies, ensuring that articles that may actually change a surgeon’s practice will be read and published. Each issue includes a brief article that will help a surgeon better understand the business of healthcare, as well as an article that will help a surgeon understand how to interpret increasingly complex research methodology. Clinical Spine Surgery is your single source for up-to-date, evidence-based recommendations for spine care.